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Artificially Expanded Genetic Information Systems (AEGIS)

The concept

  • When detecting DNA in complex biological media, uninteresting DNA can interfere.
  • In 1990, innovators at Firebird solved this problem, developing an Artificially Expanded Genetic Information System (AEGIS)TM.

By shuffling hydrogen bond donors and acceptors, the Z:P, K:X. and S:B pairs were created.

 


 

The complete AEGIS expanded alphabet. Different heterocycles implement the various AEGIS hydrogen bonding patterns. Shown are our most popular heterocycles.